Which group is considered a vulnerable population in research?

Prisoners are considered a vulnerable population in research due to their unique circumstances and limitations on their autonomy. Research involving prisoners must take into account their confined status, which can significantly affect their ability to make free choices regarding participation. This vulnerable status often results from potential coercion, where the consequences of declining to participate could be perceived as punitive or limit access to certain privileges within the prison system. Regulations governing research with prisoners, such as those from the U.S. Department of Health and Human Services, are designed to ensure that their rights and welfare are protected.

In contrast, college students, professional athletes, and research faculty typically have greater autonomy and decision-making capacity regarding their participation in research studies. They may also have more access to resources, support, and the ability to refuse participation without facing undue risk or consequences. These groups are not classified as vulnerable in the same manner as prisoners, primarily due to their enhanced ability to make informed choices about their involvement in research activities.