What is the process for submitting an appeal to the IRB after a research proposal is denied?

Submitting a written appeal that addresses the IRB's concerns is the appropriate process when a research proposal is denied. This approach allows the researcher to directly engage with the specific issues raised by the IRB during their review. The written appeal needs to systematically respond to the concerns or reasons provided for the denial, demonstrating how the researcher has addressed these issues or why the proposal should still be considered. This process upholds the standards of communication and transparency required in research practices, ensuring that the IRB can reevaluate the proposal based on a well-informed basis.

In contrast, simply resubmitting the original proposal without any changes does not demonstrate an understanding of the IRB's feedback and could lead to another denial. Requesting an in-person meeting without any written documentation is not typically part of the formal appeal process, as there needs to be a clear record addressing the IRB's concerns. Ignoring the denial and proceeding with the research would be a violation of ethical guidelines and institutional policies, risking the integrity of the research and potential repercussions for the researcher.