What is a "continuing review" in IRB research?

A "continuing review" refers to the process of ongoing evaluation of research studies that have already received initial approval from an Institutional Review Board (IRB). This evaluation is typically conducted at least annually. The purpose of continuing review is to ensure that the research continues to meet ethical standards, complies with regulations, and that any risks to participants are regularly assessed and managed appropriately. Researchers are required to provide updates and any necessary changes to their study protocols, informed consent processes, and participant data to the IRB, which reviews the findings and determines whether the study can continue as is, needs modifications, or should be terminated based on current data and ethical considerations. This systematic oversight helps protect participant welfare throughout the life of the research project.

In contrast, assessing the risks of new research projects pertains to the initial review process rather than continuing review. A final report is associated with the completion of a study, summarizing the research findings but not part of the ongoing evaluation. Lastly, a review triggered only by serious ethical issues pertains to specific circumstances rather than the routine continuing review process, which is proactive in monitoring ongoing projects.